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DeCS
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Descriptor English:
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Sex Hormone-Binding Globulin
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Descriptor Spanish:
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Globulina de Unión a Hormona Sexual
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Descriptor Portuguese:
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Globulina de Ligação a Hormônio Sexual
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Synonyms English:
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Binding Globulin, Testosterone-Estradiol
Globulin, Sex Hormone-Binding
Globulin, Testosterone-Estradiol Binding
Hormone-Binding Globulin, Sex
Sex Hormone Binding Globulin
Sex Steroid Binding Protein
Sex Steroid-Binding Protein
Steroid-Binding Protein, Sex
Testosterone Estradiol Binding Globulin
Testosterone-Estradiol Binding Globulin
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Tree Number:
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D12.776.124.790.223.800
D12.776.157.762
D12.776.377.715.182.800
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Definition English:
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A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications. |
Indexing Annotation English:
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does not refer to all sex hormones: refers to a specific protein in the blood binding only testosterone or estradiol; for other sex hormone-binding globulins consider ANDROGEN-BINDING PROTEIN & PROGESTERONE-BINDING GLOBULIN; DF: SHBG
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See Related English:
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Androgen-Binding Protein
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History Note English:
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77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92
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Allowable Qualifiers English:
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Record Number:
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22292
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Unique Identifier:
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D012738
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Occurrence in VHL:
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Similar:
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DeCS
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